WebSTATION-Berlin. Luckenwalder Str. 4–6 u000310963 Berlin. T + 49 (0)30 88 000 719 u0003F + 49 (0)30 88 000 716 u0003M [email protected] WebNov 30, 2016 · In CtsB and L double KO MEFs there is substantial accumulation of BACE1 and APP-CTFs, while the levels of fl-APP seem not to be affected by lysosomal dysfunction due to CtsB/L depletion (Fig 6C and 6D). Single KO CtsB or CtsL MEFs revealed that CtsL may be the major cysteine cathepsin involved in BACE1/APP-CTF lysosomal degradation.
Cathepsin B and D deficiency in the mouse pancreas induces
WebMar 21, 2024 · CTSB (Cathepsin B) is a Protein Coding gene. Diseases associated with CTSB include Keratolytic Winter Erythema and Annular Erythema . Among its related pathways are Collagen chain trimerization and Innate Immune System . Gene Ontology (GO) annotations related to this gene include peptidase activity and cysteine-type … WebDec 7, 2024 · cathepsin B Antibody (H-5) is an IgG 2b κ mouse monoclonal cathepsin B antibody (also designated CTSB antibody) suitable for the detection of the cathepsin B protein of mouse, rat and human origin by WB, IP, IF and ELISA. cathepsin B Antibody (H-5) is available as both the non-conjugated anti-cathepsin B antibody form, as well as … fixmeremotely
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WebSep 23, 2024 · Cathepsin B (CTSB), a member of lysosomal cathepsin, is involved in cell autophagy and apoptosis. We previously reported that CTSB increased cardiomyocyte apoptosis in mice heart during pressure overload, while the role of CTSB on diabetic cardiomyopathy has not been fully elucidated. WebMar 23, 2024 · The major lysosomal proteases, Cathepsin B (CTSB), Cathepsin D (CTSD) and Cathepsin L (CTSL), are implicated in autophagic activity. To investigate the role of each cathepsin in the exocrine ... WebFeb 29, 2016 · CTSB is inhibited by both inhibitors, CA-074Me and E64d. CA-074Me inhibits specifically, and E64d because it inhibits the thiol cathepsin group of which CTSB is a member. ... (Berlin, Germany ... fix memory management