Integrin alpha 2b
Nettet24. feb. 2024 · Integrin αIIb Antibody (B-9) is an IgG 2b κ mouse monoclonal Integrin alpha IIb antibody (also designated GP2B antibody, ITGA2B antibody, GPalpha IIb antibody or Integrin alpha-IIb antibody) that detects the Integrin alpha IIb protein of mouse, rat and human origin by WB, IP, IF, IHC(P) and ELISA. Integrin αIIb Antibody … NettetStructure. Integrins are obligate heterodimers composed of α and β subunits.Several genes code for multiple isoforms of these subunits, …
Integrin alpha 2b
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Nettet5. okt. 2024 · Abstract Integrin α IIb β 3 is a highly abundant heterodimeric platelet receptor that can transmit information bidirectionally across the plasma membrane, and … NettetIntegrin α2bβ3 signaling leads to the activation of Src family kinases, PLC gamma, PKC, and PI-3 Kinase as well as the activation of proinflammatory signaling pathways. …
Nettet15. okt. 2000 · When they encounter a subendothelial matrix exposed by injury to a vessel, platelets adhere, are activated, and become adhesive for other platelets so that they aggregate. alpha IIb/beta 3, a platelet-specific integrin, is largely prominent amongst the adhesion receptors and is essential for platelet aggregation. NettetIntegrin alpha 2b beta 3, also known as GPIIbIIIa, is the most abundant Integrin expressed by megakaryocytes and platelets, both on the surface and within alpha …
Integrin alpha-IIb is a protein that in humans is encoded by the ITGA2B gene. ITGA2B, also known as CD41, encodes integrin alpha chain 2b. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. Alpha chain 2b undergoes post-translational cleavage to yield … Se mer ITGA2B has been shown to interact with AUP1 and CLNS1A. Se mer • Cluster of differentiation • Glycoprotein IIb/IIIa Se mer • CD41+Antigen at the U.S. National Library of Medicine Medical Subject Headings (MeSH) • Overview of all the structural information available … Se mer • Bray PF (1995). "Inherited diseases of platelet glycoproteins: considerations for rapid molecular characterization". Thromb. Haemost. 72 (4): 492–502. PMID 7878622. • Naik UP, Parise LV (1997). "Structure and function of platelet alpha IIb beta 3". Curr. Opin. Hematol. 4 (5): … Se mer NettetHuman, mouse and rat cell adhesion molecule markers and antibodies. Featured Cell Adhesion Molecule Key Markers Hamster Anti-Mouse CD11c Antibody, clone N418 recognizes the murine homolog of human …
NettetTargeting of alpha 2b beta 3 by therapeutic antibodies or small molecules can inhibit formation of thrombi in patients with acute coronary syndrome, and potentially inhibits …
Nettet8. nov. 2024 · Itga2b integrin alpha 2b [ (house mouse)] Gene ID: 16399, updated on 8-Nov-2024 Summary Enables extracellular matrix binding activity. Acts upstream of or … hope 135mm rear wheelNettetIntegrin alpha 2b (ITGA2b), also known as CD41 and GPIIb, is a transmembrane glycoprotein that is expressed by megakaryocytes and platelets. It is cleaved into two disulfide-linked chains (114 kDa and 22 kDa) during transit through the Golgi. hope 17long legged shore birdNettetLaminin-binding integrins are composed of a large alpha chain in conjunction with a smaller beta1 chain (10). On muscle, integrin alpha7/beta1 is able to bind the laminins … long legged snowmanNettetIntegrins are expressed by all multicellular animals, but their diversity varies widely among species; for example, in mammals, 19 alpha and 8 beta subunit genes encode polypeptides that combine to form 25 different receptors, whereas the Drosophila and Caenorhabditis genomes encode only five and two integrin alpha subunits respectively. long legged shore bird crossword clueNettetProteintech Anti-CD41/Integrin alpha 2b Polyclonal, Catalog # 24552-1-AP. Tested in Western Blot (WB), Immunohistochemistry (Paraffin) (IHC (P)) and Immunoprecipitation (IP) applications. This antibody reacts with Human, Mouse, Rat samples. Supplied as 150 µL purified antibody (0.45 mg/mL). hope140NettetRecombinant Human Integrin alpha 2b beta 3 Protein, CF Summary Product Specifications Purity >95%, by SDS-PAGE visualized with Silver Staining and … long legged sea creature