Receptor protein-tyrosine phosphatase mu
Webb1 okt. 1995 · Lack of association between receptor protein tyrosine phosphatase RPTP mu and cadherins. Association between a transmembrane protein tyrosine phosphatase … Webb23 sep. 2008 · Receptor protein-tyrosine phosphatase that mediates homotypic cell-cell interactions and plays a role in adipogenic differentiation via modulation of p120 …
Receptor protein-tyrosine phosphatase mu
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Webb10 maj 2012 · The protein tyrosine phosphatase CD45, encoded by the PTPRC gene, is well known as a regulator of B- and T-cell receptor signaling. In addition, CD45 negatively regulates JAK family kinases downstream of cytokine receptors. Here, we report the presence of CD45 inactivating mutations in T-cell acute lymphoblastic leukemia.
Webb1 aug. 2000 · In the developing avian retinotectal system, many different receptor protein tyrosine phosphatases are expressed. Most of them have unknown functions. Retinal ganglion cells express at least three different members of this receptor family on their axons and growth cones: CRYPalpha, CRYP-2 and PTPmu. CRYPalpha interacts… Webb5 jan. 2024 · MAM; Domain in meprin, A5, receptor protein tyrosine phosphatase mu (and others) cd00063 Location: 394 → 484 FN3; Fibronectin type 3 domain; One of three …
WebbProtein tyrosine phosphatase non-receptor 12 (PTPN12) is an important protein tyrosine phosphatase involved in regulating cell adhesion and migration as well as … Webb1 apr. 2024 · Above all, U7D-1 is a selective USP7 PROTAC degrader, with a DC 50 of 33 nM in RS4;11 cells. Nonetheless, U7D-1 shows anticancer activity. U7D-1 induces apoptosis in Jeko-1 cells. Next in importance, U7D-1 induced USP7 degradation in RS4;11 cells, reducing the USP7 protein level by 83.2% at 1 μM. Particularly, U7D-1 shows anti-proliferative ...
Webb20 jan. 2015 · Receptor tyrosine kinases (RTKs), including anaplastic lymphoma kinase (ALK), are important during development and regeneration and are often aberrantly activated in cancer. ALK is an orphan RTK with no known ligand. Murray et al. found that heparin bound directly and with high affinity to a specific region in the extracellular …
WebbMAM Domain in meprin, A5, receptor protein tyrosine phosphatase mu (and others) There are 13548 MAM domains in 5639 proteins in SMART's nrdb database. Click on the … brat cookingWebbmember, the receptor protein tyrosine phosphatase mu (PTP ), functions in retinal development based on in vitro experiments. PTP mediates homophilic cell–cell adhesion … bratch wombourneWebb11 jan. 2011 · Sequence: MLSHGAGLALWITLSLLQTGLA Chain: PRO_0000025436: 23-1997: UniProt: Receptor-type tyrosine-protein phosphatase beta brat coloring sheetsWebb1 okt. 1995 · It has recently been shown that RPTP mu mediates homophilic interactions when expressed in insect cells. In this study, we have examined how RPTP mu may function as a cell contact receptor in mink lung epithelial cells, which express RPTPmu endogenously, as well as in transfected 3T3 cells. brat coloring pageReceptor-type tyrosine-protein phosphatase mu is an enzyme that in humans is encoded by the PTPRM gene. The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. Protein tyrosine phosphatases are protein enzymes that remove phosphate moieties from tyrosine residues … Visa mer Transmembrane PTPs are known as receptor protein tyrosine phosphatases (RPTPs). RPTPs are single pass transmembrane proteins usually with one or two catalytic domains in their intracellular domain … Visa mer PTPmu protein expressed on the surface of cells is able to mediate binding between two cells, which results in the clustering of the cells, known as … Visa mer Classical cadherins are important proteins for cells to bind in the body (‘’in vivo’’) where they commonly stabilize cell–cell junctions known as … Visa mer Neurite outgrowth PTPmu is expressed in the developing brain and retina. A brain cell, or neuron, has a cell body that contains the nucleus and two types of extensions or processes that grow out from the cell body, the dendrites and axons. … Visa mer There are a number of ways that RPTP catalytic activity can be regulated (for reviews, see ). Dimerization of identical RPTP proteins at the … Visa mer PTPµ is expressed in human umbilical cord vein endothelial cells (HUVEC) and in capillaries in the developing brain. The expression of PTPµ in HUVEC cells increases at higher cell density. Studies of PTPµ expression in animal tissues have demonstrated that … Visa mer PTPRM has been shown to interact with: • BCCIP, • c-Met, • CDH1 E-cadherin (Cadherin-1), • CDH2 N-cadherin (Cadherin-2), Visa mer brat clip artWebbRPTP mu is a transmembrane protein tyrosine phosphatase with an adhesion molecule-like ectodomain. It has recently been shown that RPTP mu mediates homophilic … brat cooked temperatureWebb1 jan. 2004 · The receptor-type protein tyrosine phosphatase PTP mu comprises an extracellular segment containing a MAM domain, an immunoglobulin domain and four … brat cooking time on grill